THE STUDY OF APOPTOSIS OF CELLS IN THE EXPERIMENT

Mansharipova Almagul Tuleuovna, Head of cardiology sub-department, Re-search Institute of cardiology and internal diseases (Rebublik of Kazakhstan, Almaty), dralma @mail.ru
Dzhakupova Aygyul Saruarovna, Candidate of medical sciences, Research Institute of cardiology and internal diseases (Rebublik of Kazakhstan, Almaty), aigulyk197575@mail.ru
Tokeshova Liza Eserkepovna, Researcher, “Kaznanomed” ltd., dralma @mail.ru
Safonov Dmitry Pavlovich, Junior researcher, sub-department of re-search management, Research Institute of cardiology and internal diseases (Rebublik of Kazakhstan, Almaty), galina.2005@mail.ru
Bulentaeva Zaynep Asylbekovna, Head of laboratory of molecular genetics, Institute of general genetics and cytology, Republik of Kazakhstan., zikagirl@mail.ru
Grinevich Ekaterina Evgenyevna, Researcher, “Kaznanomed” ltd., grinkath@mail.ru

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Apoptosis of cardiomyocyte in coronary insufficiency decreases the quantity of viable cardiomyocyte. This leads to decrease in cardiac contractility and progression of cardiac insufficiency. In our research influence of steroid hormones and parameters of free - radical reactions on аpoptosis of cardiomyocyte is investigated at coronary insufficiency at rats. It is revealed, that at coronary insufficiency is present disbalance hormones of a bark of adrenal glands and free-radical processes кар-диомиоцитов which cause process the аpoptosis of cardiomyocyte.

apoptosis, cardiomyocytes, corticosteron, immunohistochemistry.